DIRECT SURGERY OF ARTERIOSCLEROSIS

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Further considerations on the indications for and limitations of direct surgery in arteriosclerosis.

Segmental obstruction due to arteriosclerosis may occur in peripheral arteries. Further experience in resection of these obstructed segments and their replacement by vein grafts is reported. Replacement of segments of the femoral artery has been accomplished in 30 patients. The proper selection of patients is essential for success. The various causes of failure and the limitations of the proced...

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Experimental Arteriosclerosis

Arteriosclerotic lesions have been produced in monkeys (Macaca nemestrina) by selective removal of the vascular endothelium with an intra-arterial balloon catheter. Immediately after de-endothelialization a platelet layer covers the denuded area. This thrombus is gradually removed and by 7 days the vessel appears to be largely reendothelialized. Beginning at day 4, smooth muscle cells undergo m...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1953

ISSN: 0003-4932

DOI: 10.1097/00000658-195313830-00012